What makes your existence matter? Is to look after your family, this could be immediate and extended family in certain instances.
Relationships give us meaning, at some point we have to stop and take it all in and appreciate what we have.
Or is it that particular job or degree or losing weight that you really want? If it is starting your own business, what are you doing to make it meaningful on a daily basis. What are you doing to achieve those goals that you have?
Make this a daily challenge for yourself so that by the end of the week you know how far you have come.